A prospective study of absolute risk and determinants of human papillomavirus incidence among young women in Costa Rica.

ABSTRACT:

Background

High risk human papillomaviruses (HR-HPV) are known to be extremely common, sexually transmitted infections, but more information is needed regarding the absolute risks of type-specific HR-HPV infections in the years following sexual debut.

Methods

We conducted a survival analysis of 3,737 women aged 18-25 from the control group of the Costa Rican Vaccine trial to determine the absolute risks of HR-HPV infections at 12 months, 24 months, and end of follow-up (average of 50.7 months). To corroborate determinants of infection, we used Cox proportional hazards methods to assess associations between demographics and sexual risk behaviors and incident HR-HPV.

Results

Cumulative incidence for HR-HPV infections was 51.3% at the end of the study period. The most co

SUBMITTER: Clarke M 

PROVIDER: S-EPMC3723935 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature