MAIN software for density averaging, model building, structure refinement and validation.

ABSTRACT: MAIN is software that has been designed to interactively perform the complex tasks of macromolecular crystal structure determination and validation. Using MAIN, it is possible to perform density modification, manual and semi-automated or automated model building and rebuilding, real- and reciprocal-space structure optimization and refinement, map calculations and various types of molecular structure validation. The prompt availability of various analytical tools and the immediate visualization of molecular and map objects allow a user to efficiently progress towards the completed refined structure. The extraordinary depth perception of molecular objects in three dimensions that is provided by MAIN is achieved by the clarity and contrast of colours and the smooth rotation of the displayed o

SUBMITTER: Turk D 

PROVIDER: S-EPMC3727325 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature