Genomic characterization provides new insight into Salmonella phage diversity.

ABSTRACT:

Background

Salmonella is a widely distributed foodborne pathogen that causes tens of millions of salmonellosis cases globally every year. While the genomic diversity of Salmonella is increasingly well studied, our knowledge of Salmonella phage genomic diversity is still rather limited, despite the contributions of both lysogenic and lytic phages to Salmonella virulence, diversity and ecology (e.g., through horizontal gene transfer and Salmonella lysis). To gain a better understanding of phage diversity in a specific ecological niche, we sequenced 22 Salmonella phages isolated from a number of dairy farms from New York State (United States) and analyzed them using a comparative genomics approach.

Results

Classification of the 22 phages according to the presence/absence of ort

SUBMITTER: Moreno Switt AI 

PROVIDER: S-EPMC3728262 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature