Comparative transcriptomics in three Methylophilaceae species uncover different strategies for environmental adaptation.

ABSTRACT: We carried out whole transcriptome analysis of three species of Methylophilaceae, Methylotenera mobilis, Methylotenera versatilis and Methylovorus glucosotrophus, in order to determine which metabolic pathways are actively transcribed in cultures grown in laboratory on C1 substrates and how metabolism changes under semi-in situ conditions. Comparative analyses of the transcriptomes were used to probe the metabolic strategies utilized by each of the organisms in the environment. Our analysis of transcript abundance data focused on changes in expression of methylotrophy metabolic modules, as well as on identifying any functional modules with pronounced response to in situ conditions compared to a limited set of laboratory conditions, highlighting their potential role in environmental adaptat

SUBMITTER: Vorobev A 

PROVIDER: S-EPMC3728764 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature