Label-free virus detection using silicon photonic microring resonators.

ABSTRACT: Viruses represent a continual threat to humans through a number of mechanisms, which include disease, bioterrorism, and destruction of both plant and animal food resources. Many contemporary techniques used for the detection of viruses and viral infections suffer from limitations such as the need for extensive sample preparation or the lengthy window between infection and measurable immune response, for serological methods. In order to develop a method that is fast, cost-effective, and features reduced sample preparation compared to many other virus detection methods, we report the application of silicon photonic microring resonators for the direct, label-free detection of intact viruses in both purified samples as well as in a complex, real-world analytical matrix. As a model system, we d

SUBMITTER: McClellan MS 

PROVIDER: S-EPMC3729447 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature