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Distribution of arterial lesions in Takayasu's arteritis and giant cell arteritis.


ABSTRACT:

Objectives

To compare patterns of arteriographic lesions of the aorta and primary branches in patients with Takayasu's arteritis (TAK) and giant cell arteritis (GCA).

Methods

Patients were selected from two North American cohorts of TAK and GCA. The frequency of arteriographic lesions was calculated for 15 large arteries. Cluster analysis was used to derive patterns of arterial disease in TAK versus GCA and in patients categorised by age at disease onset. Using latent class analysis, computer derived classification models based upon patterns of arterial disease were compared with traditional classification.

Results

Arteriographic lesions were identified in 145 patients with TAK and 62 patients with GCA. Cluster analysis demonstrated that arterial involvement was conti

SUBMITTER: Grayson PC 

PROVIDER: S-EPMC3729734 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature