Ontology highlight
ABSTRACT:
SUBMITTER: Berndt SI
PROVIDER: S-EPMC3729927 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Nature genetics 20130616 8
Genome-wide association studies (GWAS) have previously identified 13 loci associated with risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify additional CLL susceptibility loci, we conducted the largest meta-analysis for CLL thus far, including four GWAS with a total of 3,100 individuals with CLL (cases) and 7,667 controls. In the meta-analysis, we identified ten independent associated SNPs in nine new loci at 10q23.31 (ACTA2 or FAS (ACTA2/FAS), P=1.22×10(-14)), ...[more]