Autoantibody prevalence in active tuberculosis: reactive or pathognomonic?

ABSTRACT: To evaluate the autoantibody in patients without corresponding symptoms, whether these autoantibody are pathognomonic or not. We hypothesised that autoantibody may be reactive to chronic infection, such as tuberculosis (TB). Randomised, case-control cohort study. A tertiary centre in Taiwan. We randomly chose 100 patients out of the data bank of patients with TB in a tertiary medical centre. All patients completed the sera sampling. We chose 100 patients according to autoantibody prevalence in previous literature. We also chose 100 medical staff as control group. We tested anti-SSA, anti-SSB, anti-Sm, anti ribonucleoprotein, anti-Scl 70, anticentromere, anti-double-stranded DNA, anticardiolipin IgG and IgM in all patient and control groups. The clinical symptoms and the underlying disease

SUBMITTER: Shen CY 

PROVIDER: S-EPMC3731725 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature