Effects of sugar-sweetened beverages on plasma acylation stimulating protein, leptin and adiponectin: relationships with metabolic outcomes.

ABSTRACT:

Objective

The effects of fructose and glucose consumption on plasma acylation stimulating protein (ASP), adiponectin, and leptin concentrations relative to energy intake, body weight, adiposity, circulating triglycerides, and insulin sensitivity were determined.

Design and methods

Thirty two overweight/obese adults consumed glucose- or fructose-sweetened beverages (25% energy requirement) with their ad libitum diets for 8 weeks, followed by sweetened beverage consumption for 2 weeks with a standardized, energy-balanced diet. Plasma variables were measured at baseline, 2, 8, and 10 weeks, and body adiposity and insulin sensitivity at baseline and 10 weeks.

Results

Fasting and postprandial ASP concentrations increased at 2 and/or 8 weeks. ASP increases correlated with c

SUBMITTER: Rezvani R 

PROVIDER: S-EPMC3732502 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature