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Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge Niphates sp.

ABSTRACT: A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.

SUBMITTER: Legrave N 

PROVIDER: S-EPMC3736423 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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Nepheliosyne B, a new polyacetylenic acid from the new caledonian marine sponge Niphates sp.

Legrave Nathalie N   Hamrouni-Buonomo Souhir S   Dufies Maeva M   Guérineau Vincent V   Vacelet Jean J   Auberger Patrick P   Amade Philippe P   Mehiri Mohamed M  

Marine drugs 20130627 7

A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines. ...[more]

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