Macular morphology and visual acuity in the comparison of age-related macular degeneration treatments trials.

ABSTRACT:

Objective

To describe the effects of treatment for 1 year with ranibizumab or bevacizumab on macular morphology and the association of macular morphology with visual acuity (VA) in eyes with neovascular age-related macular degeneration (AMD).

Design

Prospective cohort study within a randomized clinical trial.

Participants

Participants in the Comparison of Age-related Macular Degeneration Treatments Trials.

Methods

Participants were assigned randomly to treatment with ranibizumab or bevacizumab on a monthly or as-needed schedule. Optical coherence tomography (OCT), fluorescein angiography (FA), color fundus photography (FP), and VA testing were performed periodically throughout 52 weeks. Masked readers graded images. General linear models were applied to evaluat

SUBMITTER: Jaffe GJ 

PROVIDER: S-EPMC3737287 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature