Nitric oxide affects short-term olfactory memory in the antennal lobe of Manduca sexta.

ABSTRACT: Nitric oxide (NO) is thought to play an important neuromodulatory role in olfaction. We are using the hawkmoth Manduca sexta to investigate the function of NO signaling in the antennal lobe (AL; the primary olfactory network in invertebrates). We have found previously that NO is present at baseline levels, dramatically increases in response to odor stimulation, and alters the electrophysiology of AL neurons. It is unclear, however, how these effects contribute to common features of olfactory systems such as olfactory learning and memory, odor detection and odor discrimination. In this study, we used chemical detection and a behavioral approach to further examine the function of NO in the AL. We found that basal levels of NO fluctuate with the daily light cycle, being higher during the noct

SUBMITTER: Gage SL 

PROVIDER: S-EPMC3737371 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature