Subclinical macular findings in infants screened for retinopathy of prematurity with spectral-domain optical coherence tomography.

ABSTRACT:

Objective

To evaluate subclinical macular findings in premature patients at risk of retinopathy of prematurity (ROP) with the use of handheld spectral-domain optical coherence tomography (SD-OCT).

Design

Prospective, observational case series.

Participants

Forty-nine prematurely born neonates.

Methods

Forty-nine infants were imaged using a handheld SD-OCT. Images were acquired in nonsedated infants in the neonatal intensive care unit (NICU). Some patients were followed and reimaged over the course of several weeks. A total of 300 total images were acquired and evaluated for cystoid macular edema (CME) and persistence of inner retinal layers.

Main outcome measures

In vivo determination of foveal retinal lamination, image analysis, and clinical observation

SUBMITTER: Dubis AM 

PROVIDER: S-EPMC3737379 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature