Acute and posttraumatic stress symptoms in a prospective gene x environment study of a university campus shooting.

ABSTRACT:

Context

The serotonin transporter (SLC6A4) has been associated with several stress-related syndromes including posttraumatic stress disorder (PTSD). The ability to detect meaningful associations is largely dependent on reliable measures of preexisting trauma.

Objective

To study the association of genetic variants within SLC6A4 with acute and posttraumatic stress symptoms in a civilian cohort with known levels of preexisting trauma and PTSD symptoms collected prior to a shared index traumatic event.

Design

Ongoing longitudinal study.

Setting

On February 14, 2008, a lone gunman shot multiple people on the campus of Northern Illinois University in DeKalb, Illinois, killing 5 and wounding 21. As part of an ongoing longitudinal study on that campus, a cohort of fema

SUBMITTER: Mercer KB 

PROVIDER: S-EPMC3738299 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature