Metingear: a development environment for annotating genome-scale metabolic models.

ABSTRACT:

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Genome-scale metabolic models often lack annotations that would allow them to be used for further analysis. Previous efforts have focused on associating metabolites in the model with a cross reference, but this can be problematic if the reference is not freely available, multiple resources are used or the metabolite is added from a literature review. Associating each metabolite with chemical structure provides unambiguous identification of the components and a more detailed view of the metabolism. We have developed an open-source desktop application that simplifies the process of adding database cross references and chemical structures to genome-scale metabolic models. Annotated models can be exported to the Systems Biology Markup Language open interchange format.

Ava

SUBMITTER: May JW 

PROVIDER: S-EPMC3740624 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature