Delirium outcomes in a randomized trial of blood transfusion thresholds in hospitalized older adults with hip fracture.

ABSTRACT:

Objectives

To determine whether a higher blood transfusion threshold would prevent new or worsening delirium symptoms in the hospital after hip fracture surgery.

Design

Ancillary study to a randomized clinical trial.

Setting

Thirteen hospitals in the United States and Canada.

Participants

One hundred thirty-nine individuals hospitalized with hip fracture aged 50 and older (mean age 81.5 ± 9.1) with cardiovascular disease or risk factors and hemoglobin concentrations of less than 10 g/dL within 3 days of surgery recruited in an ancillary study of the Transfusion Trigger Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair.

Intervention

Individuals in the liberal treatment group received one unit of packed red bl

SUBMITTER: Gruber-Baldini AL 

PROVIDER: S-EPMC3743942 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature