Clinical and epidemiologic characteristics of norovirus GII.4 Sydney during winter 2012-13 in Beijing, China following its global emergence.

ABSTRACT:

Background

Limited information is available on the molecular epidemiology of GII.4 Sydney-associated diarrhea in China in the winter of 2012-13 during the global epidemic associated with the emergence of GII.4 Sydney.

Methods

Fecal specimens collected from 171 diarrhea outpatients (one from each) between late October 2012 and the middle of March 2013 were examined for NoV by reverse transcription-polymerase chain reaction and sequences corresponding to both the NoV partial polymerase and partial capsid regions were analyzed phylogenetically. Clinical characteristics of GII.4 Sydney cases versus other NoV-positive cases detected in a previous study were compared statistically.

Results

Twenty-six (15.2%, 26/171) outpatients with diarrhea were infected with NoV. Twenty-t

SUBMITTER: Mai H 

PROVIDER: S-EPMC3745450 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature