A dancer caught midstep: the structure of ATP-bound Hsp70.

ABSTRACT: Hsp70 ATP binding induces substrate release, but the transiency of this state has inhibited its characterization. In this issue, Kityk et al. determine the Hsp70(∗)ATP structure utilizing engineered disulfide bonds, providing insights into the workings of this essential molecular machine.

SUBMITTER: Sousa R 

PROVIDER: S-EPMC3746503 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature