Detection of the intercellular adhesion gene cluster (ica) in clinical Staphylococcus aureus isolates.

ABSTRACT: Staphylococcus aureus is a major hospital and community pathogen having the aptitude to cause a wide variety of infections in men. The ability of microorganisms to produce biofilm facilitates them to withstand the host immune response and is recognized as one factor contributing to chronic or persistent infections. It was demonstrated that the ica-encoded genes lead to the biosynthesis of polysaccharide intercellular adhesion (PIA) molecules, and may be involved in the accumulation phase of biofilm formation. Different studies have shown the decisive role of the ica gene as virulence factors in staphylococcal infections. This study was carried out to demonstrate the relationship between ica gene and production of slime layer in S. aureus strains. Sixty S. aureus strains were isolated from

SUBMITTER: Namvar AE 

PROVIDER: S-EPMC3746602 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature