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Occurrence of cyclic di-GMP-modulating output domains in cyanobacteria: an illuminating perspective.


ABSTRACT:

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Microorganisms use a variety of metabolites to respond to external stimuli, including second messengers that amplify primary signals and elicit biochemical changes in a cell. Levels of the second messenger cyclic dimeric GMP (c-di-GMP) are regulated by a variety of environmental stimuli and play a critical role in regulating cellular processes such as biofilm formation and cellular motility. Cyclic di-GMP signaling systems have been largely characterized in pathogenic bacteria; however, proteins that can impact the synthesis or degradation of c-di-GMP are prominent in cyanobacterial species and yet remain largely underexplored. In cyanobacteria, many putative c-di-GMP synthesis or degradation domains are found in genes that also harbor light-responsive signal input domai

SUBMITTER: Agostoni M 

PROVIDER: S-EPMC3747582 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature