Rapid improvement in diabetes after gastric bypass surgery: is it the diet or surgery?

ABSTRACT:

Objective

Improvements in diabetes after Roux-en-Y gastric bypass (RYGB) often occur days after surgery. Surgically induced hormonal changes and the restrictive postoperative diet are proposed mechanisms. We evaluated the contribution of caloric restriction versus surgically induced changes to glucose homeostasis in the immediate postoperative period.

Research design and methods

Patients with type 2 diabetes planning to undergo RYGB participated in a prospective two-period study (each period involved a 10-day inpatient stay, and periods were separated by a minimum of 6 weeks of wash-out) in which patients served as their own controls. The presurgery period consisted of diet alone. The postsurgery period was matched in all aspects (daily matched diet) and included RYGB surger

SUBMITTER: Lingvay I 

PROVIDER: S-EPMC3747905 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature