Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*.

ABSTRACT:

Objective

Mortality associated with acute lung injury remains high. Early identification of acute lung injury prior to onset of respiratory failure may provide a therapeutic window to target in future clinical trials. The recently validated Lung Injury Prediction Score identifies patients at risk for acute lung injury but may be limited for routine clinical use. We sought to empirically derive clinical criteria for a pragmatic definition of early acute lung injury to identify patients with lung injury prior to the need for positive pressure ventilation.

Design

Prospective observational cohort study.

Setting

Stanford University Hospital.

Patients

We prospectively evaluated 256 patients admitted to Stanford University Hospital with bilateral opacities on chest ra

SUBMITTER: Levitt JE 

PROVIDER: S-EPMC3748809 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature