Baseline differences in the HF-ACTION trial by sex.

ABSTRACT:

Background

In patients with heart failure (HF), assessment of functional capacity plays an important prognostic role. Both 6-minute walk and cardiopulmonary exercise testing have been used to determine physical function and to determine prognosis and even listing for transplantation. However, as in HF trials, the number of women reported has been small, and the cutoffs for transplantation have been representative of male populations and extrapolated to women. It is also well known that peak VO(2) as a determinant of fitness is inherently lower in women than in men and potentially much lower in the presence of HF. Values for a female population from which to draw for this important determination are lacking.

Methods

The HF-ACTION trial randomized 2,331 patients (28% women) wi

SUBMITTER: Pina IL 

PROVIDER: S-EPMC3748941 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature