The complete Campylobacter jejuni transcriptome during colonization of a natural host determined by RNAseq.

ABSTRACT: Campylobacter jejuni is a major human pathogen and a leading cause of bacterial derived gastroenteritis worldwide. C. jejuni regulates gene expression under various environmental conditions and stresses, indicative of its ability to survive in diverse niches. Despite this ability to highly regulate gene transcription, C. jejuni encodes few transcription factors and its genome lacks many canonical transcriptional regulators. High throughput deep sequencing of mRNA transcripts (termed RNAseq) has been used to study the transcriptome of many different organisms, including C. jejuni; however, this technology has yet to be applied to defining the transcriptome of C. jejuni during in vivo colonization of its natural host, the chicken. In addition to its use in profiling the abundance of annotate

SUBMITTER: Taveirne ME 

PROVIDER: S-EPMC3749233 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature