Impact of analysis methods on the reproducibility and reliability of resting-state networks.

ABSTRACT: Though previous examinations of intrinsic resting-state networks (RSNs) in healthy populations have consistently identified several RSNs that represent connectivity patterns evoked by cognitive and sensory tasks, the effects of different analytic approaches on the reliability and reproducibility of these RSNs have yet to be fully explored. Thus, the primary aim of the current study was to investigate the effect of method (independent component analyses [ICA] vs. seed-based analyses) on RSN reproducibility (independent datasets) for ICA and reliability (independent time points) in both methods using functional magnetic resonance imaging. Good to excellent reproducibility was observed in 9 out of 10 commonly identified RSNs, indicating the robustness of these intrinsic fluctuations at the gr

SUBMITTER: Franco AR 

PROVIDER: S-EPMC3749744 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature