CT-based diagnosis of diffuse coronary artery disease on the basis of scaling power laws.

ABSTRACT:

Purpose

To provide proof of concept for a diagnostic method to assess diffuse coronary artery disease (CAD) on the basis of coronary computed tomography (CT) angiography.

Materials and methods

The study was approved by the Cleveland Clinic Institutional Review Board, and all subjects gave informed consent. Morphometric data from the epicardial coronary artery tree, determined with CT angiography in 120 subjects (89 patients with metabolic syndrome and 31 age- and sex-matched control subjects) were analyzed on the basis of the scaling power law. Results obtained in patients with metabolic syndrome and control subjects were compared statistically.

Results

The mean lumen cross-sectional area (ie, lumen cross-sectional area averaged over each vessel of an epicardial coron

SUBMITTER: Huo Y 

PROVIDER: S-EPMC3750415 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature