Genomic selection using low density marker panels with application to a sire line in pigs.

ABSTRACT:

Background

Genomic selection has become a standard tool in dairy cattle breeding. However, for other animal species, implementation of this technology is hindered by the high cost of genotyping. One way to reduce the routine costs is to genotype selection candidates with an SNP (single nucleotide polymorphism) panel of reduced density. This strategy is investigated in the present paper. Methods are proposed for the approximation of SNP positions, for selection of SNPs to be included in the low-density panel, for genotype imputation, and for the estimation of the accuracy of genomic breeding values. The imputation method was developed for a situation in which selection candidates are genotyped with an SNP panel of reduced density but have high-density genotyped sires. The dams of se

SUBMITTER: Wellmann R 

PROVIDER: S-EPMC3750593 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature