Association between APOE, SCARB1, PPARα polymorphisms and serum lipids in a population of Lithuanian adults.

ABSTRACT:

Background

Dyslipidemia is one of several known risk factors for coronary heart disease, a leading cause of death in Lithuania. Blood lipid levels are influenced by multiple genetic and environmental factors. Epidemiological studies demonstrated the impact of nutrition on lipid levels within the Lithuanian population although the role of genetic factors for dyslipidemias has not yet been studied. The objective of this study was to assess the distribution of the APOE, SCARB1, PPARα genotypes in the Lithuanian adult population and to determine the relationship of these genotypes with dyslipidemia.

Methods

A cross-sectional health survey was carried out in a representative random sample of the Lithuanian population aged 25-64 (n=1030). A variety of single-nucleotide polymorphis

SUBMITTER: Smalinskiene A 

PROVIDER: S-EPMC3751123 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature