Behavioral profile of adults with Prader-Willi syndrome: correlations with individual and environmental variables.

ABSTRACT:

Background

Maladaptive behavior has been reported as a phenotypical feature in Prader-Willi syndrome (PWS). It severely limits social adaptation and the quality of life of children and adults with the syndrome. Different factors have been linked with the intensity and form of these behavioral disturbances but there is no consensus about the cause. Consequently, there is still controversy regarding management strategies and there is a need for new data.

Methods

The behavior of 100 adults with PWS attending a dedicated center was assessed using the Developmental Behavior Checklist for Adults (DBC-A) and the PWS-specific Hyperphagia Questionnaire. The DBC-A was completed separately by trained caregivers at the center and relatives or caregivers in a natural setting. Genotype, g

SUBMITTER: Jauregi J 

PROVIDER: S-EPMC3751283 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature