Ontology highlight
ABSTRACT:
SUBMITTER: Xu D
PROVIDER: S-EPMC3751609 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Genome announcements 20130822 4
Attenuated Salmonella enterica serovar Typhi strain Ty21a is an important vaccine for controlling typhoid fever and serves as an oral vector for delivering heterologous antigens. The key attenuating features of this randomly mutated strain remain in question. Genome sequencing has revealed 679 single nucleotide polymorphisms (SNPs), and will help define alterations contributing to Ty21a safety and immunogenicity. ...[more]