The effect of multiple allergen immunotherapy on exhaled nitric oxide in adults with allergic rhinitis.

ABSTRACT:

Background

There is a lack of objective measures of the clinical efficacy of allergen immunotherapy which relies on patients' perception about the effect of this treatment. We studied whether the fraction of exhaled nitric oxide is affected by multiple allergen immunotherapy in polysensitized adult subjects with allergic rhinitis. We also looked for associations between exhaled nitric oxide and subjects' demographics, symptom scores, and pulmonary function tests.

Methods

Twenty adult, polysensitized subjects with seasonal and perennial allergic rhinitis who chose to undergo allergen immunotherapy were enrolled. They were evaluated at baseline, and 4, 8, 12, 24, and 52 weeks later. Exhaled nitric oxide was reported as the mean of triplicate determinations.

Findings

Our

SUBMITTER: Columbo M 

PROVIDER: S-EPMC3751795 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature