Distinct relationships of intramuscular and subcutaneous fat with cortical bone: findings from a cross-sectional study of young adult males and females.

ABSTRACT:

Context

Intracellular fat within muscle and visceral tissue has been suggested to adversely influence bone development.

Objective

The aim of the study was to evaluate associations between im fat, as reflected by muscle density as measured by peripheral quantitative computed tomography, and cortical bone parameters in young adults.

Design/setting/participants

We conducted a cross-sectional analysis of 1703 males and 2243 females aged 17.8 years from the Avon Longitudinal Study of Parents and Children.

Outcome measures

We measured cortical bone parameters from midtibial peripheral quantitative computed tomography scans.

Results

Muscle density (inversely related to im fat) was inversely associated with periosteal circumference (PC) (beta = -0.07 [95% confid

SUBMITTER: Deere K 

PROVIDER: S-EPMC3752522 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature