Impact of genetic risk assessment on nutrition-related lifestyle behaviours.

ABSTRACT: Genetic susceptibility testing for common complex disease is a practice that is currently in clinical use. There are two types of gene mutations, and therefore, two varieties of genotype testing: deterministic and susceptibility. As the term suggests, deterministic genes determine whether or not a person will develop a given trait in mendelian fashion, such as Huntington's disease. Genotype screening for such deterministic mutations has existed for decades, and is commonly used in routine medical practice. In recent years, the sequencing of the human genome has identified several 'susceptibility genes' or genes with incomplete penetrance. Mutations in these genes may increase disease susceptibility, but are not causative for disease. Genetic susceptibility testing allows unaffected individ

SUBMITTER: Vernarelli JA 

PROVIDER: S-EPMC3756543 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature