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Amygdala volume predicts inter-individual differences in fearful face recognition.

ABSTRACT: The present study investigates the relationship between inter-individual differences in fearful face recognition and amygdala volume. Thirty normal adults were recruited and each completed two identical facial expression recognition tests offline and two magnetic resonance imaging (MRI) scans. Linear regression indicated that the left amygdala volume negatively correlated with the accuracy of recognizing fearful facial expressions and positively correlated with the probability of misrecognizing fear as surprise. Further exploratory analyses revealed that this relationship did not exist for any other subcortical or cortical regions. Nor did such a relationship exist between the left amygdala volume and performance recognizing the other five facial expressions. These mind-brain associations highlight the importance of the amygdala in recognizing fearful faces and provide insights regarding inter-individual differences in sensitivity toward fear-relevant stimuli.

SUBMITTER: Zhao K

PROVIDER: S-EPMC3756978 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Amygdala volume predicts inter-individual differences in fearful face recognition.

Zhao Ke K Yan Wen-Jing WJ Chen Yu-Hsin YH Zuo Xi-Nian XN Fu Xiaolan X

PloS one 20130829 8

The present study investigates the relationship between inter-individual differences in fearful face recognition and amygdala volume. Thirty normal adults were recruited and each completed two identical facial expression recognition tests offline and two magnetic resonance imaging (MRI) scans. Linear regression indicated that the left amygdala volume negatively correlated with the accuracy of recognizing fearful facial expressions and positively correlated with the probability of misrecognizing ...[more]

PMID: 24009767

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