Whole body composition analysis by the BodPod air-displacement plethysmography method in children with phenylketonuria shows a higher body fat percentage.

ABSTRACT:

Background

Phenylketonuria (PKU) causes irreversible central nervous system damage unless a phenylalanine (PHE) restricted diet with amino acid supplementation is maintained. To prevent growth retardation, a protein/amino acid intake beyond the recommended dietary protein allowance is mandatory. However, data regarding disease and/or diet related changes in body composition are inconclusive and retarded growth and/or adiposity is still reported. The BodPod whole body air-displacement plethysmography method is a fast, safe and accurate technique to measure body composition.

Aim

To gain more insight into the body composition of children with PKU.

Methods

Patients diagnosed with PKU born between 1991 and 2001 were included. Patients were identified by neonatal screening

SUBMITTER: Albersen M 

PROVIDER: S-EPMC3757265 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature