Characterization of microRNAs in mud crab Scylla paramamosain under Vibrio parahaemolyticus infection.

ABSTRACT:

Background

Infection of bacterial Vibrio parahaemolyticus is common in mud crab farms. However, the mechanisms of the crab's response to pathogenic V. parahaemolyticus infection are not fully understood. MicroRNAs (miRNAs) are a class of small noncoding RNAs that function as regulators of gene expression and play essential roles in various biological processes. To understand the underlying mechanisms of the molecular immune response of the crab to the pathogens, high-throughput Illumina/Solexa deep sequencing technology was used to investigate the expression profiles of miRNAs in S. paramamosain under V. parahaemolyticus infection.

Methodology/principal findings

Two mixed RNA pools of 7 tissues (intestine, heart, liver, gill, brain, muscle and blood) were obtained from V. pa

SUBMITTER: Li S 

PROVIDER: S-EPMC3758354 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature