Increased risk of cancer among azoospermic men.

ABSTRACT:

Objective

To determine whether men with azoospermia are at an elevated risk of developing cancer in the years following an infertility evaluation.

Design

Cohort study.

Setting

United States andrology clinic.

Patient(s)

A total of 2,238 men with complete records were evaluated for infertility at a single andrology clinic in Texas from 1989 to 2009.

Intervention(s)

None.

Main outcome measure(s)

Cancer incidence was determined by linkage to the Texas Cancer Registry.

Result(s)

In all, 451 men had azoospermia, and 1,787 were not azoospermic, with a mean age at infertility evaluation of 35.7 years. Compared with the general population, infertile men had a higher risk of cancer, with 29 cases observed compared with 16.7 expected (standardized inc

SUBMITTER: Eisenberg ML 

PROVIDER: S-EPMC3759541 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature