Cryptococcus gattii in the United States: genotypic diversity of human and veterinary isolates.

ABSTRACT:

Background

Cryptococcusgattii infections are being reported in the United States (US) with increasing frequency. Initially, US reports were primarily associated with an ongoing C. gattii outbreak in the Pacific Northwest (PNW) states of Washington and Oregon, starting in 2004. However, reports of C. gattii infections in patients from other US states have been increasing since 2009. Whether this is due to increasing frequency of disease, greater recognition within the clinical community, or both is currently unknown.

Methodology/principal findings

During 2005-2013, a total of 273 C. gattii isolates from human and veterinary sources in 16 US states were collected. Of these, 214 (78%) were from the Pacific Northwest (PNW) and comprised primarily the clonal C. gattii genotypes V

SUBMITTER: Lockhart SR 

PROVIDER: S-EPMC3760847 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature