Signal transducer and activator of transcription 6 polymorphism and asthma risk: a meta-analysis.

ABSTRACT:

Background

The polymorphism in the signal transducer and activators of transduction 6 (STAT6) gene has been implicated in susceptibility to asthma and aetiology of asthma, but a number of studies have reported inconclusive and ambiguous results of the association between polymorphism in STAT6 gene and asthma risk in different populations. The aim of this study is to further investigate the association between the STAT6 gene polymorphism and asthma susceptibility.

Methods

Pubmed, EMBASE, China National Knowledge Infrastructure (CNKI) Weipu Database and Wanfang Database were searched to find relevant studies. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of association.

Results

Included in this meta analysis were 14 studies invol

SUBMITTER: Li B 

PROVIDER: S-EPMC3762616 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature