Multivariate modeling of proteins related to trapezius myalgia, a comparative study of female cleaners with or without pain.

ABSTRACT: The prevalence of chronic trapezius myalgia is high in women with high exposure to awkward working positions, repetitive movements and movements with high precision demands. The mechanisms behind chronic trapezius myalgia are not fully understood. The purpose of this study was to explore the differences in protein content between healthy and myalgic trapezius muscle using proteomics. Muscle biopsies from 12 female cleaners with work-related trapezius myalgia and 12 pain free female cleaners were obtained from the descending part of the trapezius. Proteins were separated with two-dimensional differential gel electrophoresis (2D-DIGE) and selected proteins were identified with mass spectrometry. In order to discriminate the two groups, quantified proteins were fitted to a multivariate analys

SUBMITTER: Hadrevi J 

PROVIDER: S-EPMC3762788 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature