Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.

ABSTRACT: The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(II)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.

SUBMITTER: Badarau A 

PROVIDER: S-EPMC3763678 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature