Studies on the pathophysiology and genetic basis of migraine.

ABSTRACT: Migraine is a neurological disorder that affects the central nervous system causing painful attacks of headache. A genetic vulnerability and exposure to environmental triggers can influence the migraine phenotype. Migraine interferes in many facets of people's daily life including employment commitments and their ability to look after their families resulting in a reduced quality of life. Identification of the biological processes that underlie this relatively common affliction has been difficult because migraine does not have any clearly identifiable pathology or structural lesion detectable by current medical technology. Theories to explain the symptoms of migraine have focused on the physiological mechanisms involved in the various phases of headache and include the vascular and neuroge

SUBMITTER: Gasparini CF 

PROVIDER: S-EPMC3763681 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature