A second generation MRI contrast agent for imaging zinc ions in vivo.

ABSTRACT: A Zn²⁺ specific GdDOTA derivative containing two bis-(3-pyrazolyl) units was prepared and characterized. Unlike a previously reported Zn²⁺ binding agent, the new agent binds to human albumin both in the presence and absence of Zn²⁺.

SUBMITTER: De Leon-Rodriguez LM 

PROVIDER: S-EPMC3763856 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature