Factors Affecting Perceptual Threshold in Argus II Retinal Prosthesis Subjects.

ABSTRACT:

Purpose

The Argus II epiretinal prosthesis has been developed to provide partial restoration of vision to subjects blinded from outer retinal degenerative disease. Participants were surgically implanted with the system in the United States and Europe in a single arm, prospective, multicenter clinical trial. The purpose of this investigation was to determine which factors affect electrical thresholds in order to inform surgical placement of the device.

Methods

Electrode-retina and electrode-fovea distances were determined using SD-OCT and fundus photography, respectively. Perceptual threshold to electrical stimulation of electrodes was measured using custom developed software, in which current amplitude was varied until the threshold was found. Full field stimulus light thres

SUBMITTER: Ahuja AK 

PROVIDER: S-EPMC3763895 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature