Cortisol response to operative stress with anesthesia in healthy children.

ABSTRACT:

Background

Supraphysiological "stress dosing" is generally given to adrenally insufficient patients undergoing operative procedures and/or general anesthesia. However, the normal responses of cortisol to surgery are poorly documented, especially in small children. Recent studies in adults suggest that massive glucocorticoid dosing is not needed, especially in minimally invasive surgery.

Objective

We sought to characterize the normal cortisol secretion rate in healthy children undergoing minimally and moderately invasive urological procedures.

Design and setting

This was a prospective observational study conducted at a tertiary referral center.

Patients

Thirty healthy children, ages 5 months to 6 years, were studied undergoing elective urological procedures.

SUBMITTER: Taylor LK 

PROVIDER: S-EPMC3763975 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature