SOX9 duplication linked to intersex in deer.

ABSTRACT: A complex network of genes determines sex in mammals. Here, we studied a European roe deer with an intersex phenotype that was consistent with a XY genotype with incomplete male-determination. Whole genome sequencing and quantitative real-time PCR analyses revealed a triple dose of the SOX9 gene, allowing insights into a new genetic defect in a wild animal.

SUBMITTER: Kropatsch R 

PROVIDER: S-EPMC3765313 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature