Oral food challenge to wheat: a near-fatal anaphylaxis and review of 93 food challenges in children.

ABSTRACT:

Background

Wheat allergy is among the most common food allergy in children, but few publications are available assessing the risk of anaphylaxis due to wheat.

Methods

In this study, we report the case of near-fatal anaphylaxis to wheat in a patient undergoing an oral food challenge (OFC) after the ingestion of a low dose (256 mg) of wheat. Moreover, for the first time, we analyzed the risk of anaphylaxis during an OFC to wheat in 93 children, compared to other more commonly challenged foods such as milk, egg, peanuts, and soy in more than 1000 patients.

Results

This study, which includes a large number of OFCs to wheat, shows that wheat is an independent risk factor that is associated with anaphylaxis requiring epinephrine administration (Odds Ratio [OR] = 2.4) and an

SUBMITTER: Cianferoni A 

PROVIDER: S-EPMC3765891 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature