Synthesis of a highly functionalized core of verrillin.

ABSTRACT: An efficient stereoselective synthesis of furanoverrillin (5), a highly functionalized core of verrillin (1), is reported. The synthetic strategy is based on constructing bicyclic lactone 17 prior to the 10-membered ring macrocyclization. The effect of the C4 methyl group on the furan reactivity is also discussed.

SUBMITTER: Saitman A 

PROVIDER: S-EPMC3766406 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature