Lewis base directed cycloaddition reactions of 2-pyrones and alkynylaluminum reagents.

ABSTRACT: In situ generated alkynylaluminum reagents have been utilized in a [4 + 2] cycloaddition with 2-pyrones bearing a Lewis basic donor. The reactions proceed at or below room temperature and with complete regiocontrol. This one-pot method affords diversely substituted aromatic compounds under very mild conditions.

SUBMITTER: Crepin DF 

PROVIDER: S-EPMC3766945 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature