Impact of endoscopic surveillance on mortality from Barrett's esophagus-associated esophageal adenocarcinomas.

ABSTRACT:

Background & aims

Although patients with Barrett's esophagus commonly undergo endoscopic surveillance, its effectiveness in reducing mortality from esophageal/gastroesophageal junction adenocarcinomas has not been evaluated rigorously.

Methods

We performed a case-control study in a community-based setting. Among 8272 members with Barrett's esophagus, we identified 351 esophageal adenocarcinoma: 70 in persons who had a prior diagnosis of Barrett's esophagus (who were eligible for surveillance); 51 of these patients died, 38 as a result of the cancers (cases). Surveillance histories were contrasted with a sample of 101 living persons with Barrett's esophagus (controls), matched for age, sex, and duration of follow-up evaluation.

Results

Surveillance within 3 years was n

SUBMITTER: Corley DA 

PROVIDER: S-EPMC3767470 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature